Pharmaceutical Organic Chemistry 2 Notes | B Pharmacy 3rd Semester Noteskarts Notes
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Pharmaceutical Organic Chemistry 2 Notes | B Pharmacy 3rd Semester Noteskarts Notes The course covers a variety of topics, including:
Unit-1: Benzene and its derivatives:
- Analytical, synthetic and other evidences in the derivation of structure of benzene, Orbital picture, resonance in benzene, aromatic characters, Huckel’s rule
- Reactions of benzene – nitration, sulphonation, halogenationreactivity, Friedelcrafts alkylation– reactivity, limitations, Friedelcrafts acylation.
- Substituents, effect of substituents on reactivity and orientation of mono substituted benzene compounds towards electrophilic substitution reaction
- Structure and uses of DDT, Saccharin, BHC and Chloramine
Unit-2: Phenol, Aromatic Amines, Aromatic Acids:
- Phenol* – Acidity of phenols, effect of substituents on acidity, qualitative tests, Structure and uses of phenol, cresols, resorcinol, naphthols
- Aromatic Amines* – Basicity of amines, effect of substituents on basicity, and synthetic uses of aryl diazonium salts
- Aromatic Acids* – Acidity, effect of substituents on acidity and important reactions of benzoic acid.
Unit-3: Fats and Oils:
- Fatty acids – reactions. Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying oils.
- Analytical constants – Acid value, Saponification value, Ester value, Iodine value, Acetyl value, Reichert Meissl (RM) value – significance and principle involved in their determination.
Unit-4: Polynuclear hydrocarbons:
- Synthesis, reactions
- Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane, Triphenylmethane and their derivatives
Unit-5: Cyclo alkanes:
- Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory, Coulson and Moffitt’s modification, Sachse Mohr’s theory (Theory of strainless rings), reactions of cyclopropane and cyclobutane only
Syllabus
Unit-1: Benzene and its derivatives:
Unit-2: Phenol, Aromatic Amines, Aromatic Acids:
Unit-3: Fats and Oils:
Unit-4: Polynuclear hydrocarbons:
Unit-5: Cyclo alkanes:
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